Polyamines as modulators of lipoperoxidation.
نویسندگان
چکیده
The polyamines spermine and spermidine and the diamine putrescine inhibit lipid peroxidation in phospholipid liposome suspensions and rat liver homogenates. Using the chemiluminescence technique the antioxidant activity of polyamines was found to be due to reactions with the free radical intermediates of lipid peroxidation and/or superoxide radicals. Also, the antioxidant action of polyamines correlated with the amount of their amino groups: the antioxidant activity increases from putrescine to spermine.
منابع مشابه
Differential effects of paraquat on oxidative stress parameters and polyamine levels in two freshwater invertebrates.
Paraquat is still a widely used herbicide in several countries. Its toxic action on plants occurs through a one-electron reduction interfering with the photosynthesis process. By a similar reaction, the herbicide may induce peroxidation processes in non-target animal species. Furthermore, paraquat may interfere with the cellular transport of polyamines. The aim of this work was to investigate s...
متن کاملPolyamine blockade promotes antitumor immunity
The levels of polyamines are elevated in neoplastic lesions as compared with normal tissues, and cancer cells tend to manifest a robust dependence on these compounds for proliferation and survival. We have recently demonstrated that a novel approach to polyamine depletion suppresses tumor growth in a T cell-dependent manner, highlighting a poorly appreciated role of polyamines as strong modulat...
متن کاملPolyamines as redox homeostasis regulators during salt stress in plants
The balance between accumulation of stress-induced polyamines and reactive oxygen species (ROS) is arguably a critical factor in plant tolerance to salt stress. Polyamines are compounds, which accumulate in plants under salt stress and help maintain cellular ROS homeostasis. In this review we first outline the role of polyamines in mediating salt stress responses through their modulation of red...
متن کاملPolyamine inhibiidon of lipoperoxidation
Polyamines appear to inhibit peroxidation of vesicles containing acidic phospholipids. A correlation exists between polyamine binding to phospholipid vesicles and its protective effect. However, phosphatidylinositolcontaining vesicles which bind spermine are not protected by the poyamine [Tadolini, Cabrini, Landi, Varani & Pasquali (1985) Biogenic Amines 3, 97-106]. In the present paper I teste...
متن کاملPhytochemical and Morphophysiological Responses in Basil (Ocimum basilicum L.) Plant to Application of Polyamines
Background: The application of polyamines as a plant growth substance with effect on a wide range of plant growth and development processes include cell division, flowering, senescence delay, membrane stability, absorb active radicals and different stress tolerance and polyamines Function as a anti-senescence and anti-stress agents in the plant and on the other hand the competitiveness of their...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- General physiology and biophysics
دوره 11 2 شماره
صفحات -
تاریخ انتشار 1992